Alzheimer's Research

Placenta accreta spectrum (PAS) disorders have become a significant life-threatening disease with rising incidence and high maternal-fetal morbidity and mortality. Imaging plays a crucial role in prenatal detection of these...

1.Rocchi, A., Pellegrini, S., Siciliano, G. & Murri, L. Causative and susceptibility genes for Alzheimer’s disease: a review. Brain Res. Bull. 61, 1–24 (2003).2.Bertram, L., McQueen, M. B., Mullin, K., Blacker, D. & Tanzi,...

ChemistryAll commercially available compounds were used without further purification. Melting points were determined on a Köfler apparatus. Analytical thin-layer chromatography (TLC) was performed on silica gel 60 F254 on aluminium plates (Merck) and visualized...

Causal structure discovery algorithmsInformally, causation is defined as a relationship between two variables X and Y such that changes in X lead to changes in Y8. The key difference between association and causation lies...

The following post is authored by Matthew Bucknor, MD, associate chair for wellbeing and professional climate, in the UC San Francisco Department of Radiology and Biomedical Imaging to announce the...

We examined the pathological relationships between microglia, associated cytokines, and AD pathologies within the dorsolateral frontal cortex in a community-based aging cohort of 154 participants from the Framingham Heart Study. Associations between inflammatory markers...

For women in particular, cardiac MRI helps achieve diagnosis and further guide management of treatment in patients with heart disease. Women are often misdiagnosed, and the trend of their misdiagnosis...

Protein preparationThe Aβ was purchased from American peptide (Aβ 1–42, 1.0 mg). 1 mg of amyloid pure peptide was dissolved in 100% 1, 1, 1, 3, 3, 3-Hexafluoro-2-propanol (HFIP) to a concentration of 2 mg/ml and incubated...

Patients with dementia develop dysphagia some time during the clinical course of their disease. The aim of this study was to compare the swallowing functions of the 2 most common types of dementia: Alzheimer...

1.Alzheimer’s Association Alzheimer’s Disease Facts and Figures. Alzheimer’s & Dementia, 13(4), 325–373, ISSN 1552–5260, https://doi.org/10.1016/j.jalz.2017.02.001 (2017).2.Jack, C. R. Jr. et al. NIA-AA Research Framework: Toward a biological definition of Alzheimer’s disease. Alzheimers Dement 14,...