Delirium and Behavioral Symptoms in Persons With Dementia at Hospital Admission: Mediating Factors
Background:
Hospitalized persons with dementia are at risk of delirium with behavioral symptoms, predisposing them to a higher rate of complications and caregiver distress. The purpose of this study was to examine the relationship...
MRI Safety Practices: “Every Minute, Every Day”
UCSF Radiology & Biomedical Imaging strives to ensure patient safety in all our imaging modalities, and this includes providing patients with the highest level of MR safety. MR Safety is overseen by the MR...
Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive...
arising from: C. Gouveia et al.; Scientific Reports https://doi.org/10.1038/s41598-022-12391-2 (2022).Gouveia and colleagues (2022)1 conducted a genome-wide association study (GWAS) of a polygenic risk score (PRS)-derived phenotype (N = 37,784), in which they identified 246 independent loci...
The Associations Between Intracranial Stenosis, Brain Amyloid-beta, and Cognition in a Memory Clinic Sample
Background:
Intracranial stenosis (ICS) and brain amyloid-beta (Aβ) have been associated with cognition and dementia. We aimed to investigate the association between ICS and brain Aβ and their independent and joint associations with cognition.
Methods:...
Gray Matter Volume as Evidence for Cognitive Reserve in Bilinguals With Mild Cognitive Impairment
Background:
Compared with monolinguals, bilinguals have a later onset of mild cognitive impairment (MCI) and Alzheimer disease symptoms and greater neuropathology at similar cognitive and clinical levels. The present study follows a previous report...
Modulating heart rate oscillation affects plasma amyloid beta and tau levels in younger and...
Baseline characteristics of participantsThe male and female ratio was similar across age groups and conditions (Table 1). At baseline, in neither age cohort did the Osc+ and Osc− groups differ significantly in plasma Aβ, plasma...
Dr. Olga Tymofiyeva authors “Just City” science-fiction novel
About ten years ago, soon after she had moved to the United States, Olga Tymofiyeva, PhD, associate professor in the UCSF Department of Radiology and Biomedical Imaging, watched a lecture...
Celebrating the Accomplishments of Women at UCSF Radiology
It's always a good time of year to recognize and celebrate the many women who contribute their talent and expertise to the UC San Francisco Department of Radiology and Biomedical Imaging. On...
Protein fibril length in cerebrospinal fluid is increased in Alzheimer’s disease
Parnetti, L. et al. CSF and blood biomarkers for Parkinson’s disease. Lancet Neurol. 18, 573–586 (2019).Article
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Dr. Olga Tymofyeva authors “Just City” science-fiction novel
About ten years ago, soon after she had moved to the United States, Olga Tymofiyeva, PhD, associate professor in the UCSF Department of Radiology and Biomedical Imaging, watched a lecture...
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Brain Focused Ultrasound: A New Era of Image-guided Neuro-intervention
A UCSF team that includes members of the Department of Radiology and Biomedical Imaging, is addressing new clinical and research neuro...
Compound limits magnesium transport in cellular power plants called mitochondria. — ScienceDaily
Researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have developed a small-molecule drug that prevents weight...
Neuroinflammation predicts cognitive decline in FTD
Microglial activation in the frontal cortex is predictive of future cognitive decline in individuals with frontotemporal dementia (FTD), according to a new study. The...