New origin of deep brain waves discovered
University of California, Irvine biomedical engineering researchers have uncovered a previously unknown source of two key brain waves crucial for deep sleep: slow waves and sleep spindles. Traditionally believed to originate from one brain...
New technique sheds light on memory and learning
Less than twenty minutes after finishing this article, your brain will begin to store the information that you've just read in a coordinated burst of neuronal activity. Underpinning this process is a phenomenon known...
UCSF Breast Imaging Experts Advise Annual Screening Mammograms
The U.S. Preventive Services Task Force (USPSTF) recommends that women begin breast cancer screening mammograms at age 40 and continue to have mammograms every two years (biennially) thereafter. Bonnie Joe, MD,...
Five biomarkers from one cerebrospinal fluid sample to stage Alzheimer’s disease
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.This is a summary of: Salvadó, G. et al. Disease staging of Alzheimer’s disease using a CSF-based biomarker...
Adenosine triphosphate induces amorphous aggregation of amyloid β by increasing Aβ dynamics
Sample preparation for DXBAβ was dissolved in 0.1% NH4OH/1 mM DMSO to a concentration of 0.1 mg/mL. ATP, ADP, and AMP (10 mM) were added to the Aβ solution and reacted at 37 °C for 0 min, 30 min, 1 day,...
Advanced Imaging of Peripheral Pain Generators
Imaging at 0.55, 1.5, and 3.0 Tesla. The main magnetic field strength of clinical MRI scanners has shifted from 1.5 Tesla to 3 Tesla over the past decades. This is...
Loss of Smell is a Precursor to Cognitive Impairment in Gulf War Veterans
After the 1991 Gulf War, many veterans came home reporting a variety of medically unexplained symptoms that were initially called Gulf War Syndrome, but has come to be known today...
Multi-modal Neuroimaging Phenotyping of Mnemonic Anosognosia in the Aging Brain
Lenzoni, S., Morris, R. G. & Mograbi, D. C. The Petrified Self 10 Years After: Current Evidence for Mnemonic anosognosia. Front. Psychol. 11, https://doi.org/10.3389/fpsyg.2020.00465 (2020).Chapman, S. et al. Mnemonic monitoring in anosognosia for memory...
Biannual Mammogram are not Frequent Enough
The U.S. Preventive Services Task Force (USPSTF) currently recommends that women begin breast cancer screening mammograms at age 40 and receive them biannually thereafter. Bonnie Joe, MD, PhD, Division Chief...
Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer’s disease
Cohort characteristicsWe performed cross-sectional and longitudinal analyses in four independent cohorts. Cohort-1 was the Dementia Disease Initiation (DDI, Norwegian national multicenter study) cohort (n = 364) which longitudinally follows older adults who were CN (n = 221) or...
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Take it from the rats: A junk food diet can cause long-term damage to...
A new USC-led study on rats that feasted on a high-fat, sugary diet raises the possibility that a junk food-filled diet in teens may...
Repurposing non-pharmacological interventions for Alzheimer’s disease through link prediction on biomedical literature
The complete workflow is depicted in Fig. 1. To investigate the association between NPIs and AD, we initially conducted preprocessing and integration of biomedical triples...
Degenerative Dementias and Their Medical Care in the Movies
Compared with other neurologic problems, few films have been dedicated to degenerative dementia. To our knowledge, this is the first systematic review about the...