Alzheimer's Research

1.Nature News Round-up. Swine flu snipers, Alzheimer’s drug push and Google’s latest gaming bot. Nature 574 602–603 (2019).2.Rabinovici, G. D. et al. Association of amyloid positron emission tomography with subsequent change in clinical management...

1.Goate, A. et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer’s disease. Nature 349, 704–706 (1991).2.Sherrington, R. et al. Cloning of a gene bearing missense mutations in...

1.Petersen, R. C. et al. Prevalence of mild cognitive impairment is higher in men. The Mayo Clinic Study of Aging. Neurol. 75, 889–897 (2010).2.Tschanz, J. T. et al. Conversion to dementia from mild cognitive...

The fear of developing Alzheimer disease (AD) is highly salient, particularly for biologic family members. The current study evaluated social/cognitive explanations for perceived AD threat beyond genetic relatedness, including personal experience with AD, belief...

APOE*ε4 promotes synucleinopathy Read more...

Weight loss is a frequent complication of Alzheimer disease (AD), associated with increased morbidity and mortality. Increased appetite and weight gain are known side effects of the antidepressant mirtazapine. This analysis was undertaken to...

Dual-energy CT (DECT) is not new, in fact, says Benjamin Yeh, MD, it has been around just as long as computed tomography (CT) has. What is new is that CT...

Optimization of culture conditions for long-term primary neurons culture in 96-well microplateTo determine appropriate culture conditions for high-throughput imaging of endogenous fluorescent synapses in live primary neurons, we performed a systematic comparison and optimization...

Abstract: This study aims to compare patient- and proxy-rated utilities and health-related quality of life from individuals in different stages of Alzheimer disease (AD). Two hundred seventy-two patients and their primary caregivers were enrolled in...

In this study, we present a comprehensive evaluation of two brain segmentation methods using three atlas databases. We present detailed descriptive data comparing three commonly used atlas databases and show that the databases differ...