Background: Despite substantial progress made in the past decades, the pathogenesis of sporadic Alzheimer disease (sAD) and related biological markers of the disease are still controversially discussed. Cerebrospinal fluid and functional brain imaging markers...

ParticipantsIn this cross-sectional study, we included N = 121 participants (Fig. 5; Table 1 for demographic description) from the study Remote Assessment of Disease and Relapse – Alzheimer’s Disease (RADAR-AD). Inclusion criteria were community-dwelling adults older...

In this section we first discuss findings for the MFCC2 feature, followed by observations about higher-order MFCCs.The acoustic spectra in Fig. 2 show that (especially in the FTD cohort) differences between cases and controls are...

Murley, A. G. et al. Redefining the multidimensional clinical phenotypes of frontotemporal lobar degeneration syndromes. Brain 143, 1555–1571 (2020).Article  PubMed  PubMed Central  ...

Researchers at LMU, the Max Planck Institute for Human Development, and the University of Oxford have investigated how sleep affects memory. They found a link between breathing and the emergence of certain brain activity...

Improvement of dementia diagnosis and risk stratification is of critical importance as the population continues to age. Unraveling temporally antecedent risk factors and health event trajectories has the potential to improve our understanding of...

An interdisciplinary team consisting of researchers from the Center for Cognition and Sociality and the Data Science Group within the Institute for Basic Science (IBS) revealed a striking similarity between the memory processing of...

Ethical approvalWe declare that all methods were performed in accordance with the relevant guidelines and regulations. The Institutional Review Board (IRB) of the Asan Medical Center waived the need for informed consent for the...

Aaa, A. 2022 Alzheimer’s disease facts and figures. Alzheimer’s Dement. 18(4), 700–789. https://doi.org/10.1002/ALZ.12638 (2022).Article  ...

Measurement protocolThe data collection followed the guidelines established by the Declaration of Helsinki and all participants signed informed consent letter prior to the measurements. All measurements took place in Oulu University Hospital, Oulu, Finland....