Imaging Cortical Bone Vasculature | UCSF Radiology
A decade ago, Thomas Link, MD, PhD, was senior author on a paper in J Bone Miner Res1 that suggested that severe deficits in cortical bone quality are responsible for...
The Promise of Mid-Field MRI
Magnetic Resonance Imaging (MRI), plays a pivotal role in healthcare, determining treatment paths and eligibility for procedures like hip or knee replacements. Yet, approximately 90% of the global population lacks...
A decade of aphantasia research: what we’ve learned about people who can’t visualize
People who can't visualise an image in their mind's eye are less likely to remember the details of important past personal events or to recognise faces, according to a review of nearly ten years...
Influences of amyloid-β and tau on white matter neurite alterations in dementia with Lewy...
McKeith, I. G. et al. Diagnosis and management of dementia with Lewy bodies: third report of the DLB consortium. Neurology 65, 1863–1872 (2005).CAS
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Blended antioxidant supplement improves cognition and memory in aged mice
Cell damage from oxidative stress is a major underlying cause of age-related cognitive and muscle strength decline. Antioxidants can reduce oxidative stress and prevent age-related health decline. A new study has found that mice...
Hyperpolarized Imaging Techniques for the Kidney, Brain, and Pancreas
Two studies from the UCSF Department of Radiology and Biomedical Imaging and the Hyperpolarized MRI Technology Resource Center (HMTRC) highlight new methods to better image cancer in the kidney, brain,...
Welcoming Thomas Yohannan, MD, to UCSF’s Molecular Imaging & Therapeutics Division
The University of California, San Francisco (UCSF) Department of Radiology and Biomedical Imaging is pleased to welcome Thomas Yohannan, MD, to the Molecular Imaging & Therapeutics division as Associate Professor.
Dr. Yohannan...
Amyloid-β prediction machine learning model using source-based morphometry across neurocognitive disorders
Hardy, J. A. & Higgins, G. A. Alzheimer’s disease: The amyloid cascade hypothesis. Science 256, 184–185 (1992).Article
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Single-nucleus RNA velocity reveals critical synaptic and cell-cycle dysregulations in neuropathologically confirmed Alzheimer’s disease
Data origin and single-nucleus RNA velocity estimationSingle nucleus RNA-seq data was obtained from the prefrontal cortex of 48 postmortem human brain samples1 (Sects. “Methods”, “Dataset-1”). Twenty-four of these individuals had no or low β-amyloid...
Traumatic Brain Injury: Emergency Radiologists at ZSFG are the Frontline of Patient Care
March marks Brain Injury Awareness Month, which is dedicated to prevention and advancements in care and research. Jason Talbott, MD, PhD, emergency radiology chief at Zuckerberg San Francisco General Hospital (ZSFG),...
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Take it from the rats: A junk food diet can cause long-term damage to...
A new USC-led study on rats that feasted on a high-fat, sugary diet raises the possibility that a junk food-filled diet in teens may...
Repurposing non-pharmacological interventions for Alzheimer’s disease through link prediction on biomedical literature
The complete workflow is depicted in Fig. 1. To investigate the association between NPIs and AD, we initially conducted preprocessing and integration of biomedical triples...
Degenerative Dementias and Their Medical Care in the Movies
Compared with other neurologic problems, few films have been dedicated to degenerative dementia. To our knowledge, this is the first systematic review about the...