Deep learning application for the classification of Alzheimer’s disease using 18F-flortaucipir (AV-1451) tau positron...
SubjectsA total of 271 subjects (138 CU, 75 MCI, and 63 AD) in the Alzheimer’s Disease Neuroimaging Initiative (ADNI3) for whom 18F-flortaucipir PET scans were performed at baseline were recruited. Age, sex, education, Mini-Mental...
Association of gout with brain reserve and vulnerability to neurodegenerative disease
Kuo, C.-F., Grainge, M. J., Zhang, W. & Doherty, M. Global epidemiology of gout: prevalence, incidence and risk factors. Nat. Rev. Rheumatol. 11, 649–662 (2015).Article
PubMed
...
USPSTF’s Proposed Breast Cancer Screening Guidelines prompt comments from UCSF Breast Imaging faculty Bonnie...
On May 9, the U.S. Preventive Services Task Force (USPSTF) proposed a significant change to current breast cancer screening guidelines. The USPSTF’s draft proposal recommends lowering the recommended breast cancer...
USPSTF’s Proposed Breast Cancer Screening Guidelines
USPSTF’s Proposed Breast Cancer Screening Guidelines prompt comments from UCSF Breast Imaging faculty Bonnie Joe, MD, PhD, and Kimberly Ray, MD
On May 9, the U.S. Preventive Services Task Force (USPSTF)...
Predictive network analysis identifies JMJD6 and other potential key drivers in Alzheimer’s disease
Cerejeira, J., Lagarto, L. & Mukaetova-Ladinska, E. B. Behavioral and psychological symptoms of dementia. Front. Neurol. 3, 73 (2012).Article
CAS
PubMed
PubMed Central
...
Robots can help find objects you’ve lost, thanks to new ‘artificial memory’ — ScienceDaily
Engineers at the University of Waterloo have discovered a new way to program robots to help people with dementia locate medicine, glasses, phones and other objects they need but have lost.
And while the initial...
Transcriptomic and glycomic analyses highlight pathway-specific glycosylation alterations unique to Alzheimer’s disease
Jack, C. R. et al. NIA-AA research framework: Toward a biological definition of Alzheimer’s disease. Alzheimer’s Dement. 14, 535–562 (2018).Article
...
Brain proteomic analysis implicates actin filament processes and injury response in resilience to Alzheimer’s...
Clinico-pathologic groupsThis research was ethically approved by the University of Washington Institutional Review Board (IRB) and the Stanford University IRB. All study cohort participants provided informed consent under protocols approved by these IRBs. Sex...
Overlap in Frontotemporal Atrophy Between Normal Aging and Patients With Frontotemporal Dementias
Normal aging leads to frontocortical atrophy. The degree to which this complicates the use of frontotemporal atrophy as a diagnostic criterion for the frontotemporal dementias (FTDs) has not been reported. The present case-control study...
UCSF’s Hyperpolarized MRI Technology Resource Center (HMTRC) hosts its 9th International HP Technology Workshop
On April 13-14th 2023, the HMTRC celebrated its 11th year as a center and its annual Workshop continues to have a national and global impact on the advancement of hyperpolarized...
Latest article
Targeted metabolomic analysis in Parkinson’s disease brain frontal cortex and putamen with relation to...
GBD 2016 Parkinson’s Disease Collaborators. Global, regional, and national burden of Parkinson’s disease, 1990–2016: A systematic analysis for the Global Burden of Disease Study...
The hippocampus plays a crucial role in assigning positive value through interactions with others...
Researchers from the Center for Cognition and Sociality (CCS) within the Institute for Basic Science (IBS) recently announced the discovery of neurons that allow...
Neural cell state shifts and fate loss in ageing and age-related diseases
Zhao, N. et al. Alzheimer’s risk factors age, APOE genotype, and sex drive distinct molecular pathways. Neuron 106, 727–742 (2020).Article
CAS
...