Meet Chemist & Metabolic Imaging Expert Celine Taglang, PhD
“What I find most meaningful about my work as a researcher is fulfilling my search for knowledge and curiousity,” said Celine Taglang, PhD, a researcher in the Cancer Metabolic Imaging...
Blocking key protein may halt progression of Alzheimer’s disease
Researchers at the University of Colorado Anschutz Medical Campus have found that inhibiting a key protein can stop the destruction of synapses and dendritic spines commonly seen in Alzheimer's disease.
The study, whose first author...
Leveraging electronic health records and knowledge networks for Alzheimer’s disease prediction and sex-specific biological...
2022 Alzheimer’s disease facts and figures. Alzheimers Dement. 18, 700–789 (2022).Rasmussen, J. & Langerman, H. Alzheimer’s disease – why we need early diagnosis. Degener. Neurol. Neuromuscul. Dis. 9, 123–130 (2019).PubMed
PubMed...
Genome-wide epistasis analysis reveals gene–gene interaction network on an intermediate endophenotype P-tau/Aβ42 ratio in...
Pang, C. et al. Identification and analysis of Alzheimer’s candidate genes by an amplitude deviation algorithm. J. Alzheimer’s Dis. Parkinson. 9 (2019).Abdullah, M. N., Wah, Y. B., Majeed, A. B. A., Zakaria, Y. & Shaadan,...
Alterations in Cholesterol and Ganglioside GM1 Content of Lipid Rafts in Platelets From Patients...
The aim of this study was to investigate the changes in the protein, cholesterol, and ganglioside GM1 content of lipid rafts in platelets from patients with Alzheimer disease (AD), and identify potential blood biomarkers...
Are you depressed? Scents might help
Smelling a familiar scent can help depressed individuals recall specific autobiographical memories and potentially assist in their recovery, discovered a team of University of Pittsburgh School of Medicine researchers and UPMC social workers in...
Reduced progranulin increases tau and α-synuclein inclusions and alters mouse tauopathy phenotypes via glucocerebrosidase
AnimalsAll protocols were approved by Yale Institutional Animal Care and Use Committee (IACUC) (2023-07281).Human P301S tau transgenic (PS19) mice with B6C3F1 background34 were obtained from the Jackson Laboratory. The mice express mutant human MAPT...
The Carer Assessment of MedicaTion Management GuidanCe for People With Dementia at Hospital Discharge...
Purpose:
The Carer Assessment of medicaTion management guidanCe for people with dementia at Hospital discharge (CATCH) tool was developed to examine the carer’s experiences of medication management guidance delivery at discharge. This study explored...
The brain is ‘programmed’ for learning from people we like
Our brains are "programmed" to learn more from people we like -- and less from those we dislike. This has been shown by researchers in cognitive neuroscience in a series of experiments.
Memory serves a...
Blood protein markers predict 15-year risk of dementia
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.This is a summary of: Guo, Y. et al. Plasma proteomic profiles predict future dementia in healthy adults....
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