Welcome, Incoming 2025 Residents! | UCSF Radiology
We are delighted to welcome 15 new residents, who matched to our diagnostic radiology and integrated IR residency programs and will join UCSF Department of Radiology and Biomedical Imaging in...
A single nuclear transcriptomic characterisation of mechanisms responsible for impaired angiogenesis and blood-brain barrier...
Endothelial cells are enriched in genes associated with genetic risk for ADOur analyses were based on data from 77 cortical brain samples from donors with AD (n = 41) or non-diseased controls (NDC, n = 36). Three different...
A blood-based biomarker workflow for optimal tau-PET referral in memory clinic settings
Participant characteristicsA total of 548 participants in the BioFINDER-2 cohort met the criteria to be included in the present analysis based on the availability of at least one of the plasma biomarkers listed below...
Identification of clinical disease trajectories in neurodegenerative disorders with natural language processing
Identification of neuropsychiatric signs and symptoms and exploration of the labeled dataWe have established a computational pipeline that consists of text parsers and NLP models to convert the extensive medical record summaries into clinical...
Insights from Turkey’s big data: unraveling the preventability, pathogenesis, and risk management of Alzheimer’s...
In recent years, significant advancements have been made in understanding the pathogenesis of Alzheimer's disease (AD) through the accumulation and monitoring of biomarkers, shedding light on the accumulation and prevalence of AD pathology. Blood...
Researchers identify gene involved in neuronal vulnerability in Alzheimer’s disease
Early stages of neurodegenerative disorders are characterized by the accumulation of proteins in discrete populations of brain cells and degeneration of these cells. For most diseases, this selective vulnerability pattern is unexplained, yet it...
Ultrasound-Guided Injection Relieves Pain, Enables Mom to Care for Newborn
Maryana was over-the-moon to be a mom for the first time when she learned she was pregnant in May 2022. Energetic and lively, Maryana was taken by surprise when she...
A noninvasive treatment for ‘chemo brain’
Patients undergoing chemotherapy often experience cognitive effects such as memory impairment and difficulty concentrating -- a condition commonly known as "chemo brain."
MIT researchers have now shown that a noninvasive treatment that stimulates gamma frequency...
Transfer Learning: Detecting Multiple Sclerosis Lesions with Artificial Intelligence Trained on Other Pathologies
When AI leverages large amounts of data it can be used to produce diagnostic tools that help locate abnormalities faster and more accurately. However, for patients with diseases like multiple...
Sex-specific associations of serum cortisol with brain biomarkers of Alzheimer’s risk
Participants and dataThis is a natural history, non-interventional study of cognitively normal individuals ages 35–65 years, carrying risk factors for late-onset AD such as a family history and/or APOE4 genotype. Participants were recruited at the...
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Take it from the rats: A junk food diet can cause long-term damage to...
A new USC-led study on rats that feasted on a high-fat, sugary diet raises the possibility that a junk food-filled diet in teens may...
Repurposing non-pharmacological interventions for Alzheimer’s disease through link prediction on biomedical literature
The complete workflow is depicted in Fig. 1. To investigate the association between NPIs and AD, we initially conducted preprocessing and integration of biomedical triples...
Degenerative Dementias and Their Medical Care in the Movies
Compared with other neurologic problems, few films have been dedicated to degenerative dementia. To our knowledge, this is the first systematic review about the...