Age-specific and Sex-specific Prevalence and Incidence of Mild Cognitive Impairment, Dementia, and Alzheimer Dementia...
As the population ages, the need to characterize rates of cognitive impairment and dementia within demographic groups defined by age, sex, and race becomes increasingly important. There are limited data available on the prevalence...
TRPV1 regulates ApoE4-disrupted intracellular lipid homeostasis and decreases synaptic phagocytosis by microglia
Human brain samplesHuman postmortem tissues from control and AD patients were obtained from the Netherlands Brain Bank (Netherlands Institute for Neuroscience, Amsterdam, Netherlands). Written informed consent for brain autopsy specimens for research purposes after...
An action plan to prevent Alzheimer’s disease — ScienceDaily
Memory loss, behavioural changes, cognitive deficits: Alzheimer's disease leads to a dramatic loss of autonomy for those affected and has a heavy impact on health costs. Its prevention has become a real social challenge....
Events serve as ‘stepping stones’ en route to retrieved memories — ScienceDaily
One solution to this frustratingly common scenario is to retrace your steps. This can be done by physically moving through the space where you suspect your elusive keychain is hiding or, as explored in...
Dr. Amanda Baker, UCSF Clinical Fellow, Awarded ASPNR Travel Grant
We are excited to congratulate Amanda Baker, MD, for receiving the Charlotte and Thierry Huisman Travel Grant Award. Dr. Baker, a Diagnostic and Interventional Neuroradiology Fellow at the UC San Francisco...
Our memory for objects might be better than we think — ScienceDaily
The next time you're struggling to remember exactly where you left your keys, parked your car or put down your glasses, don't necessarily give up on your memory completely. Previous research has shown that,...
Research Assessing Bone Quality and Marrow Adiposity in People Living with HIV
People living with HIV (PLWH) have increased risk of osteoporosis and fractures. As PLWH live longer through effective antiretroviral therapy (ART) we see that HIV-related bone loss is superimposed upon...
Why do we remember emotional events better? — ScienceDaily
Columbia Engineering neuroscientists identified a specific neural mechanism in the human brain that tags information with emotional associations for enhanced memory. The team demonstrated that high-frequency brain waves in the amygdala, a hub for...
MRI data-driven clustering reveals different subtypes of Dementia with Lewy bodies
In this study, we expanded previous hypothesis-driven MRI subtyping studies in DLB by conducting a data-driven MRI subtyping. We included a relatively large multi-center cohort including countries from Europe and the US. We found...
SIRT6 is a key regulator of mitochondrial function in the brain
López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The Hallmarks of Aging. Cell. 2013;153:1194–217.
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