Alzheimer's Research

Today, patients with prostate cancer can be effectively treated with surgery, radiation, or androgen deprivation therapy. However, a significant fraction of patients progress to metastatic, castration-resistant prostate cancer (mCRPC), which...

2021 Alzheimer’s disease facts and figures. Alzheimers Dement 17, 327–406 (2021).Mucke, L. Neuroscience: Alzheimer’s disease. Nature 461, 895–897 (2009).Article  CAS  PubMed  ...

Debate exists regarding differences in the prevalence of Alzheimer disease (AD) in African Americans and Hispanics in the United States, with some evidence suggesting that the prevalence of AD may be considerably higher in...

On March 24, the Bay Area Young Investigators Meeting for Nuclear Imaging and Therapy met as part of the annual COBRA series. COBRA, The Bay Area Community Of Bay area...

Anil Bidkar, PhD, a postdoctoral fellow in the department of radiology and biomedical imaging, has received the Department of Defense (DoD) Prostate Cancer Research Program (PCRP) Early Investigator Research Award....

Demographic and clinical characteristicsCognitively normal elderly participants (CN), patients with mild cognitive impairment due to AD (MCI-AD), and patients with mild dementia due to AD (MD-AD) did not differ according to education, depressive symptoms...

Tissue samplesSeven human brain hemispheres (six left, one right) were acquired from the Massachusetts General Hospital Autopsy Suite (45–84 years; 68.33 ± 14.39 (mean ± sd); four males, two females, one unknown; postmortem intervals < 24 h). Autopsy consent was obtained from...

From the UCSF OMOP-based EMR database (>5 million patients), we identified 7409 patients with AD (Supplementary Fig. 1) and 14,818 PS-matched control patients. After a second round of PS-matching to obtain subcohorts of racialized populations,...

DatasetData used in the preparation of this article were obtained from the ADNI. The ADNI was launched in 2003 as a public–private partnership, led by Principal Investigator Michael W. Weiner, MD. The primary goal...

People with Alzheimer's disease develop defects in cognitive functions like memory as well as problems with noncognitive functions that can lead to anxiety and depression. In a paper published April 6 in the journal...