Sunday, November 24, 2024

Blood biomarker-based classification study for neurodegenerative diseases

The diagnosis of AD and PD are still challenging tasks in clinical practice, partly due to the lack of accessible and accurate blood biomarkers. Here, different classification algorithms were applied to transcriptomics data to...

ApoE attracts microglia to amyloid-β plaques

The cell adhesion molecule VCAM1 directs microglia towards ApoE-associated amyloid-β (Aβ) plaques, leading to Aβ clearance, according to new research published in Nature Aging. The results of the study highlight this signalling pathway as...

Predicting cognitive decline in a low-dimensional representation of brain morphology

Figure 1 shows a diagram of the data processing pipeline used for this research, described in more detail in the following section.Figure 1Methodological pipeline for the prediction of cognitive outcome. (1) We separate the different...

In forming long-term memories, vascular cells are crucial

Research on long-term memories has largely focused on the role of neurons -- the brain's nerve cells. However, in recent years, scientists are discovering that other cell types are also vital in memory formation...

Protein p53 regulates learning, memory, sociability in mice

Researchers have established the protein p53 as critical for regulating sociability, repetitive behavior, and hippocampus-related learning and memory in mice, illuminating the relationship between the protein-coding gene TP53 and neurodevelopmental and conditions like autism...

Saturated fat may interfere with creating memories in aged brain

New research hints at a few ways fatty foods affect cells in the brain, a finding that could help explain the link between a high-fat diet and impaired memory -- especially as we age. The...

RIDR Summer Intern Symposium 2023

Eighteen student interns from the 2023 RIDR cohort – including 5 high school students, 2 undergraduate college students, and 11 medical school students – presented their final research projects at...

For Some Prostate Cancer Patients, PSMA PET May Be Better for Initial Staging of...

A recent article in the Journal of Nuclear Medicine reports findings of a multi-center retrospective study that compares bone scan with PSMA PET for initial staging of prostate cancer. Authors include UCSF...

UCSF Radiology Welcomes Three New Faculty Members

We are excited to welcome three new faculty members to the University of California, San Francisco (UCSF) Department of Radiology and Biomedical Imaging. With Dr. Kang Wang's background in MRI technology...

Brain signals for good memory performance revealed

People differ significantly in their memory performance. Researchers at the University of Basel have now discovered that certain brain signals are related to these differences. While it is well known that certain brain regions play...
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