In forming long-term memories, vascular cells are crucial

Research on long-term memories has largely focused on the role of neurons — the brain’s nerve cells. However, in recent years, scientists are discovering that other cell types are also vital in memory formation and storage.

A new study, published in the journal Neuron, reveals the crucial role of vascular system cells — known as pericytes — in the formation of long-term memories of life events — memories that are lost in diseases such as Alzheimer’s disease. The research, conducted by New York University neuroscientists, shows that pericytes, which wrap around the capillaries — the body’s small blood vessels — work in concert with neurons to help ensure that long-term memories are formed.

“We now have a firmer understanding of the cellular mechanisms that allow memories to be both formed and stored,” says Cristina Alberini, a professor in New York University’s Center for Neural…

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