Alzheimer's Research

Depression is one of the most common mental illnesses in the world, but current anti-depressants have yet to meet the needs of many patients. Neuroscientists from City University of Hong Kong (CityU) recently discovered...

Gorelick, P. B. et al. Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 42, 2672–2713 (2011). An overall guide for practitioners to...

Memory, a fundamental tool for our survival, is closely linked with how we encode, recall, and respond to external stimuli. Over the past decade, extensive research has focused on memory-encoding cells, known as engram...

As millions of Americans struggle with memory loss and dementia brought on by increasingly common neurodegenerative disorders, like Alzheimer's disease and Parkinson's disease, greater understanding of how the brain works and is affected in...

Neuroscientists have discovered a fascinating connection between the retention of early life memories and brain developmental trajectories associated with autism. Most of us remember little of our experiences from before two years of age. This...

Faculty researchers in the UCSF Department of Radiology and Biomedical Imaging have received six NIH diversity supplements over the past year, critical support for achieving our vision of a diverse...

Characteristics of the participants in discovery and replication analysesA flowchart of the primary analyses is presented in Fig. 1. In the discovery analysis, the total sample size was 7277 from three cohorts. The mean age...

Each year, during the first week of November, we observe National Radiologic Technology Week (NRTW) to recognize and celebrate our imaging technologists. This event showcases the important contributions that medical...

Global transcriptional changes induced by medin, Aβ, and NL in HBMVECsTo investigate molecular impact of medin on HBMVECs, three independent sets of seven treatment groups of HBMVECs were prepared and analyzed by RNA-seq, which...

Boosted endogenous fructose production and metabolism in the hippocampus of db/db micePeriodic measurements of cognitive status demonstrated marked and persistent cognitive dysfunction in db/db mice compared with the m/m mice at 24 weeks (Supplementary...