Sunday, May 19, 2024

Utility of the Repeat and Point Test for Subtyping Patients With Primary Progressive Aphasia

Background: Primary progressive aphasia (PPA) may present with three distinct clinical sybtypes: semantic variant PPA (svPPA), nonfluent/agrammatic variant PPA (nfvPPA), and logopenic variant PPA (lvPPA). Objective: The aim was to examine the utility of the...

Associated with better locational awareness, verbal fluency, and working memory — ScienceDaily

Taking a regular afternoon nap may be linked to better mental agility, suggests research published in the online journal General Psychiatry. It seems to be associated with better locational awareness, verbal fluency, and working memory,...

Tau induces PSD95–neuronal NOS uncoupling and neurovascular dysfunction independent of neurodegeneration

1.Cummings, J., Lee, G., Ritter, A. & Zhong, K. Alzheimer’s disease drug development pipeline: 2018. Alzheimers Dement. (NY) 4, 195–214 (2018). ...

Identification of potential blood biomarkers for early diagnosis of Alzheimer’s disease through immune landscape...

Albert, M. S. et al. The diagnosis of mild cognitive impairment due to Alzheimer’s disease: recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimers Dement. 7, 270–279...

‘ study reveals how exercise helps maintain memory function during aging — ScienceDaily

A new study provides novel insight into the benefits of exercise, which should motivate adults to keep moving throughout their lifetime, especially during middle age. Long-term exercise profoundly benefits the aging brain and may...

Information and Competency for Consent to Pharmacologic Clinical Trials in Alzheimer Disease: An Empirical...

Summary: This study was undertaken to evaluate (1) what information normal and Alzheimer disease (AD) participants are able to manage; (2) the correlation between the degree of competency and age, education and dementia scores, and...

Trends in Alzheimer Disease Mortality Among American Indian and Alaska Native People Between 2011...

Purpose: The number of American Indian and Alaska Native (AI/AN) people living with dementia is expected to increase 5-fold by 2060. Social determinants of health may explain disparities in the incidence of Alzheimer disease...

Breast Cancer Survivor Advocates for Screening and Early Detection

When 53-year-old photographer and single mom Pia Navales went to the Berkeley Outpatient Center for her annual mammogram in December 2021, she had no reason to suspect any problems. "I...

Intracellular amyloid toxicity induces oxytosis/ferroptosis regulated cell death

All reagents were obtained from Sigma-Aldrich (St. Louis, MO, USA), unless otherwise stated.Intracellular amyloid toxicity in MC65 nerve cellsThe MC65 nerve cells were obtained from Dr. L. W. Jin (UC Davis). The induction of...
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Take it from the rats: A junk food diet can cause long-term damage to...

A new USC-led study on rats that feasted on a high-fat, sugary diet raises the possibility that a junk food-filled diet in teens may...

Repurposing non-pharmacological interventions for Alzheimer’s disease through link prediction on biomedical literature

The complete workflow is depicted in Fig. 1. To investigate the association between NPIs and AD, we initially conducted preprocessing and integration of biomedical triples...

Degenerative Dementias and Their Medical Care in the Movies

Compared with other neurologic problems, few films have been dedicated to degenerative dementia. To our knowledge, this is the first systematic review about the...