Sunday, May 19, 2024

Scientists discover that the resting brain repeatedly replays compressed memories of what was just...

In a study of healthy volunteers, National Institutes of Health researchers have mapped out the brain activity that flows when we learn a new skill, such as playing a new song on the piano,...

Quinacrine directly dissociates amyloid plaques in the brain of 5XFAD transgenic mouse model of...

ReagentsAβ(1–42) peptides were synthesized using solid-phase peptide synthesis as previously reported13. Thioflavin T (ThT, catalog# T3516), dimethyl sulfoxide (DMSO, catalog# D8418), BSA (bovine serum albumin, catalog# A3059-100G), RIPA buffer (radio immunoprecipitation assay buffer, catalog#...

Alzheimer Special Care Units Compared With Traditional Nursing Home for Dementia Care: Are There...

Background Studies comparing Alzheimer Special Care Units (ASCUs) with traditional nursing homes (NHs) have reported conflicting results. Objectives To compare the characteristics and the effects on mortality, hospitalization, use of physical restraints, falls, and antipsychotics...

Attenuation of Choroidal Thickness in Patients With Alzheimer Disease: Evidence From an Italian Prospective...

Introduction: To compare the 12-month choroidal thickness (CT) change between Alzheimer disease (AD) patients and normal subjects. Methods: In this prospective, observational study, 39 patients with a diagnosis of mild to moderate AD and 39...

A new role of the ventral striatum explains habitual seeking behavior — ScienceDaily

Researchers have been investigating how the brain controls habitual seeking behaviors such as addiction. A recent study by Professor Sue-Hyun Lee from the Department of Bio and Brain Engineering revealed that a long-term value...

Electrical stimulation of the nucleus basalis of meynert: a systematic review of preclinical and...

1.Kuhn, J. et al. Deep brain stimulation of the nucleus basalis of Meynert in Alzheimer’s dementia. Mol. Psychiatry 20, 353–360 (2015).CAS  PubMed  Article  PubMed Central  ...

Abnormal brain cholesterol homeostasis in Alzheimer’s disease—a targeted metabolomic and transcriptomic study

Participants: BLSAThe BLSA is a prospective cohort study that began at the National Institute on Aging (NIA) in 195859,60.Evaluations are scheduled every two years. As of 2003 participants over the age of 80 are...

Visual impairment increases the risk of dementia, especially in young males in a 12-year...

1.Lin, M. Y. et al. Vision impairment and combined vision and hearing impairment predict cognitive and functional decline in older women. J. Am. Geriatr. Soc. 52, 1996–2002. https://doi.org/10.1111/j.1532-5415.2004.52554.x (2004).Article  PubMed  ...

Intermittent fasting in mice demonstrably more effective at promoting long term memory retention —...

A new study from the Institute of Psychiatry, Psychology and Neuroscience (IoPPN) at King's College London has established that Intermittent Fasting (IF) is an effective means of improving long term memory retention and generating...

Memory details fade over time, with only the main gist preserved — ScienceDaily

What information is retained in a memory over time, and which parts get lost? These questions have led to many scientific theories over the years, and now a team of researchers at the Universities...
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Take it from the rats: A junk food diet can cause long-term damage to...

A new USC-led study on rats that feasted on a high-fat, sugary diet raises the possibility that a junk food-filled diet in teens may...

Repurposing non-pharmacological interventions for Alzheimer’s disease through link prediction on biomedical literature

The complete workflow is depicted in Fig. 1. To investigate the association between NPIs and AD, we initially conducted preprocessing and integration of biomedical triples...

Degenerative Dementias and Their Medical Care in the Movies

Compared with other neurologic problems, few films have been dedicated to degenerative dementia. To our knowledge, this is the first systematic review about the...