Tuesday, May 7, 2024

Saturated fatty acids have emerged as key players in forming memories — ScienceDaily

Saturated fatty acid levels unexpectedly rise in the brain during memory formation, according to research, opening a new avenue of investigation into how memories are made. Dr Tristan Wallis, from Professor Frederic Meunier's laboratory at...

Higher CSF sTNFR1-related proteins associate with better prognosis in very early Alzheimer’s disease

Department of Neurology and Center for Neurodegenerative Diseases, School of Medicine, Emory University, Atlanta, GA, USAWilliam T. Hu, Tugba Ozturk, Alexander Kollhoff, J. Christina Howell, Allan I. Levey & James J. LahNell Hodgson School of Nursing, Emory University, Atlanta, GA,...

Using a Digital Neuro Signature to measure longitudinal individual-level change in Alzheimer’s disease: the...

Study designWe conducted two experiments (Study A and Study B) to assess Altoida DNS against a set of established NPs as baseline. Study A (ClinicalTrials.gov Identifier: NCT02050464) was a semi-naturalistic observational study that included...

KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s...

Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, GermanyJulia Neitzel, Nicolai Franzmeier, Anna Rubinski, Martin Dichgans, Rainer Malik & Michael EwersDepartment of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the NetherlandsJulia NeitzelDepartment of...

Interaction between genetic predisposition, smoking, and dementia risk: a population-based cohort study

1.WHO. The epidemiology and impact of dementia: current state and future trends. Document WHO/MSD/MER/15.3. http://www.who.int/mental_health/neurology/dementia/dementia_thematicbrief_epidemiology.pdf (2015).2.Livingston, G. et al. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. Lancet 396, 413–446. https://doi.org/10.1016/S0140-6736(20)30367-6...

Effects of the Insulin Sensitizer Metformin in Alzheimer Disease: Pilot Data From a Randomized...

Epidemiological studies have identified a robust association between type II diabetes mellitus and Alzheimer disease (AD), and neurobiological studies have suggested the presence of central nervous system insulin resistance in individuals with AD. Given...

Widely known as crucial for long-term memory, hippocampus also supports short-term memory — ScienceDaily

Scientists have long known the brain's hippocampus is crucial for long-term memory. Now a new Northwestern Medicine study has found the hippocampus also plays a role in short-term memory and helps guide decision-making. The findings...

Examining Leukemia Risks Among Children with Down Syndrome

Down syndrome is one of the most common genetic conditions in the U.S. and Canada. According to the Centers for Disease Control and Prevention (CDC), about 6,000 babies with Down...

T32 Radiology Fellows Share Their Experiences: Kirti Magudia, MD, PhD and Tyler Gleason, MD

2. What was your primary T32 research project? KM: My project was to develop and validate deep learning tools to predict clinically significant prostate cancer from prostate MRI using a variety...
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Take it from the rats: A junk food diet can cause long-term damage to...

A new USC-led study on rats that feasted on a high-fat, sugary diet raises the possibility that a junk food-filled diet in teens may...

Repurposing non-pharmacological interventions for Alzheimer’s disease through link prediction on biomedical literature

The complete workflow is depicted in Fig. 1. To investigate the association between NPIs and AD, we initially conducted preprocessing and integration of biomedical triples...

Degenerative Dementias and Their Medical Care in the Movies

Compared with other neurologic problems, few films have been dedicated to degenerative dementia. To our knowledge, this is the first systematic review about the...