Neural prosthetic device can help humans restore memory
A team of scientists from Wake Forest University School of Medicine and the University of Southern California (USC) have demonstrated the first successful use of a neural prosthetic device to recall specific memories.
The findings...
Epilepsy and epileptiform activity in late-onset Alzheimer disease: clinical and pathophysiological advances, gaps and...
Jack, C. R. Jr et al. NIA-AA research framework: toward a biological definition of Alzheimer’s disease. Alzheimers Dement. 14, 535–562 (2018).Article
PubMed
PubMed Central
...
Oxytocin: the love hormone that holds the key to better memory
Oxytocin (OXT) is a hormone that is known for its effects on psychological well-being and emotional bonding in animals. Interestingly, research has shown that this natural chemical in the brain plays a crucial role...
CRISPR/Cas9-mediated knock-in cells of the late-onset Alzheimer’s disease-risk variant, SHARPIN G186R, reveal reduced NF-κB...
Gatz M, Reynolds CA, Fratiglioni L, Johansson B, Mortimer JA, Berg S, et al. Role of genes and environments for explaining Alzheimer disease. Arch Gen Psychiatry. 2006;63:168.Article
PubMed
...
The structure of tyrosine-10 favors ionic conductance of Alzheimer’s disease-associated full-length amyloid-β channels
Membrane channel forming activities of the peptidesVoltage clamp experiments have been conducted at selected hold voltages between +100 mV and −100 mV (the sign corresponds to the trans side, where the peptide was added). At...
Plasma proteomic profiles predict future dementia in healthy adults
Scheltens, P. et al. Alzheimer’s disease. Lancet 397, 1577–1590 (2021).Article
CAS
PubMed
PubMed Central
...
Amyloid-β aggregates activate peripheral monocytes in mild cognitive impairment
Ethical oversight of animal and human experimentsAll animal experimentation was conducted following approval by local authorities of the Federal State of Berlin (X9007/17). All test animals lived in standardized conditions where temperature, humidity, and...
Cortical folding correlates to aging and Alzheimer’s Disease’s cognitive and CSF biomarkers
Structural MRI imaging biomarkers have been extensively studied, including cortical folding aspects of Alzheimer’s Disease23 and Mild Cognitive Impairment24. However, investigating cortical morphological measurements (or their combinations) is not straightforward since only a few...
Improving quality of life and sleep in people with memory problems without using drugs
A groundbreaking study from the University of Pennsylvania School of Nursing (Penn Nursing), recently published in Innovation in Aging, has shown promising results in improving the quality of life (QOL) and sleep quality in...
Fatty acids hold clue to creating memories
Researchers at the University of Queensland have revealed the crucial role of saturated fatty acids in the brain's consolidation of memories.
Dr Isaac Akefe from UQ's Queensland Brain Institute has uncovered the molecular mechanism and...
