Saturday, November 23, 2024

Machine learning models identify predictive features of patient mortality across dementia types

Cohort characteristics and patient mortality across dementia typesData for this study was obtained from the National Alzheimer’s Coordinating Center (NACC) database13, which spans 39 past and present Alzheimer’s Disease Centers (ADCs) across the United...

Osteocyte-derived sclerostin impairs cognitive function during ageing and Alzheimer’s disease progression

Piehl, N. et al. Cerebrospinal fluid immune dysregulation during healthy brain aging and cognitive impairment. Cell 185, 5028–5039 (2022).Article  CAS  PubMed  PubMed Central  ...

Identifying Stigmatizing Language Used by Israelis and Germans With a Mild Neurocognitive Disorder, Their...

Objectives: The purpose of the study was to examine and compare the dementia-related discourse and language used by people with mild neurocognitive disorder (MND), their family members, and family caregivers of people with Alzheimer’s...

Mendelian randomization reveals apolipoprotein B shortens healthspan and possibly increases risk for Alzheimer’s disease

Study overviewTo implement MR, we integrated summary statistics (Table 1) from various genome-wide association (GWA) studies. Figure 1 contains an overview of our approach. First, we started by integrating the GWA studies for circulating metabolites (using...

Ultrasound and antibodies — a potentially powerful combination for Alzheimer disease therapy

Golde, T. E. Open questions for Alzheimer’s disease immunotherapy. Alzheimers Res. Ther. 6, 3 (2014).Article  PubMed  PubMed Central  ...

Thank a Resident and Fellow Day

Meet our residents and fellows, read notes of appreciation from leadership, and join us in saying “thank you!” on Thank a Resident and Fellow Day, February 23, 2024. “My deepest gratitude...

Sleep improves ability to recall complex events

Sleep helps consolidate our memory of complex associations, thus supporting the ability to complete memories of whole events. Researchers had known for some time that sleep consolidates our memories of facts and episodic events. However,...

Exploring the association between cancer and cognitive impairment in the Australian Imaging Biomarkers and...

Characteristics of the study populationA total of 2136 participants were included in the present study, including 1297 (60.7%) CU, 217 (10.2%) MCI, 369 (17.3%) AD and 253 (11.8%) PRO (Table 1). Within the PRO...

The Predictive Power of Multiparametric MRI in Breast Cancer

Wen Li, PhD associate professional researcher at the Department of Radiology and Biomedical Imaging at UCSF, is first author of “Breast Multiparametric MRI for Prediction of Neoadjuvant Chemotherapy Response in...

Genetic analysis of the X chromosome in people with Lewy body dementia nominates new...

Armstrong, M. J. Lewy Body Dementias. Continuum 25, 128–146 (2019).PubMed  Google...
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