Tuesday, November 26, 2024

Clinical relevance of animal models in aging-related dementia research

Alzheimer’s Association. 2020 Alzheimer’s disease facts and figures. Alzheimers Dement. 16, 391–460 (2020).Sengupta, U. & Kayed, R. Amyloid β, tau, and α-synuclein aggregates in the pathogenesis, prognosis, and therapeutics for neurodegenerative diseases. Prog. Neurobiol....

Detection and treatment of Alzheimer’s disease in its preclinical stage

Knopman, D. S. et al. Alzheimer disease. Nat. Rev. Dis. Primers 7, 33 (2021).Article  PubMed  PubMed Central  ...

Towards a future where Alzheimer’s disease pathology is stopped before the onset of dementia

WHO. Global Status Report on the Public Health Response to Dementia. Report No. ISBN 978-92-4-003324-5 (World Health Organization, 2021).Gustavsson, A. et al. Global estimates on the number of persons across the Alzheimer’s disease continuum....

New mass spectrometry method to simultaneously quantify several tau species in blood

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.This is a summary of: Montoliu-Gaya, L. et al. Mass spectrometric simultaneous quantification of tau species in plasma...

Deep learning application for the classification of Alzheimer’s disease using 18F-flortaucipir (AV-1451) tau positron...

SubjectsA total of 271 subjects (138 CU, 75 MCI, and 63 AD) in the Alzheimer’s Disease Neuroimaging Initiative (ADNI3) for whom 18F-flortaucipir PET scans were performed at baseline were recruited. Age, sex, education, Mini-Mental...

Association of gout with brain reserve and vulnerability to neurodegenerative disease

Kuo, C.-F., Grainge, M. J., Zhang, W. & Doherty, M. Global epidemiology of gout: prevalence, incidence and risk factors. Nat. Rev. Rheumatol. 11, 649–662 (2015).Article  PubMed  ...

USPSTF’s Proposed Breast Cancer Screening Guidelines prompt comments from UCSF Breast Imaging faculty Bonnie...

On May 9, the U.S. Preventive Services Task Force (USPSTF) proposed a significant change to current breast cancer screening guidelines. The USPSTF’s draft proposal recommends lowering the recommended breast cancer...

USPSTF’s Proposed Breast Cancer Screening Guidelines

USPSTF’s Proposed Breast Cancer Screening Guidelines prompt comments from UCSF Breast Imaging faculty Bonnie Joe, MD, PhD, and Kimberly Ray, MD  On May 9, the U.S. Preventive Services Task Force (USPSTF)...

Predictive network analysis identifies JMJD6 and other potential key drivers in Alzheimer’s disease

Cerejeira, J., Lagarto, L. & Mukaetova-Ladinska, E. B. Behavioral and psychological symptoms of dementia. Front. Neurol. 3, 73 (2012).Article  CAS  PubMed  PubMed Central  ...

Robots can help find objects you’ve lost, thanks to new ‘artificial memory’ — ScienceDaily

Engineers at the University of Waterloo have discovered a new way to program robots to help people with dementia locate medicine, glasses, phones and other objects they need but have lost. And while the initial...
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