Targeted metabolomic analysis in Parkinson’s disease brain frontal cortex and putamen with relation to...
GBD 2016 Parkinson’s Disease Collaborators. Global, regional, and national burden of Parkinson’s disease, 1990–2016: A systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 17, 939–953 (2018).Article
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The hippocampus plays a crucial role in assigning positive value through interactions with others...
Researchers from the Center for Cognition and Sociality (CCS) within the Institute for Basic Science (IBS) recently announced the discovery of neurons that allow us to recognize others. The research team discovered that the...
Neural cell state shifts and fate loss in ageing and age-related diseases
Zhao, N. et al. Alzheimer’s risk factors age, APOE genotype, and sex drive distinct molecular pathways. Neuron 106, 727–742 (2020).Article
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Researchers also report first direct evidence supporting main theory for how human memory is...
While it's known that sleep plays a crucial role in strengthening memory, scientists are still trying to decode how this process plays out in the brain overnight.
New research led by scientists at UCLA Health...
β2-Microglobulin boosts β-amyloid aggregation and neurotoxicity in an Alzheimer’s disease model
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.This is a summary of: Zhao, Y. et al. β2-Microglobulin coaggregates with Aβ and contributes to amyloid pathology...
Three UCSF Radiology Researchers to present their Research at ISMRM 2023
Three UCSF Radiology researchers have received Surbeck Travel Awards to present their research at the International Society for Magnetic Resonance in Medicine (ISMRM) annual meeting. The recipients — Matthew Gibbons,...
Peripheral immune cell imbalance is associated with cortical beta-amyloid deposition and longitudinal cognitive decline
Baseline characteristics and group comparisons for the overall cohort are shown in Table 1. Compared to the NC group, the MCI group was younger (mean ± SD: MCI 73 ± 7.6 vs. NC 75 ± 5.7 years, p < 0.001) and had a...
Low-flavanol diet drives age-related memory loss, large study finds — ScienceDaily
A large-scale study led by researchers at Columbia and Brigham and Women's Hospital/Harvard is the first to establish that a diet low in flavanols -- nutrients found in certain fruits and vegetables -- drives...
Selenoprotein P concentrations and risk of progression from mild cognitive impairment to dementia
Vinceti, M. et al. Selenium neurotoxicity in humans: Bridging laboratory and epidemiologic studies. Toxicol Lett 230, 295–303. https://doi.org/10.1016/j.toxlet.2013.11.016 (2014).Article
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Influence of White Matter Hyperintensities on the Cognition of Patients With Parkinson Disease
Background
White matter hyperintensities (WMH) have been associated with cognitive impairment in elderly persons and in patients with Alzheimer disease. However, the role of WMH in Parkinson disease (PD) dementia remains to be elucidated.
Methods...
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