The sense of order distinguishes humans from other animals
Remembering the order of information is central for a person when participating in conversations, planning everyday life, or undergoing an education. A new study, published in the scientific journal PLoS One, shows that this...
Dopaminergic and noradrenergic nuclei relate to different memory types in older adults
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.This is a summary of: Dahl, M. J. et al. The integrity of dopaminergic and noradrenergic brain regions...
Met and Unmet Needs of Older Adults With Cognitive Impairment, and Burden and Benefits...
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This study examined the association between met and unmet needs of older adults with cognitive impairment living in the community and unique types of caregiving experience, each comprising different levels of caregiving burden...
Editorial by Dr. Amie Lee on Using Pre-operative MRI to Predict Potential for Nipple-Sparing...
Amie Lee, MD, contributed an editorial to Radiology, the journal of the Radiological Society of North America (RSNA) titled “Nipple-sparing Mastectomy in the Era of Neoadjuvant Systemic Therapy: The Accuracy...
Discoveries on memory mechanisms could unlock new therapies for Alzheimer’s and other brain diseases
Scientists at the University of Colorado Anschutz Medical Campus have made a 'paradigm shifting' discovery on the mechanisms required for learning and memory that could lead to new therapies for Alzheimer's disease and potentially...
A two-step workflow based on plasma p-tau217 to screen for amyloid β positivity with...
ParticipantsIn this cross-sectional study, we included patients with MCI from two independent cohorts, based on complete availability of plasma p-tau217, CSF Aβ42/Aβ40, Aβ-PET and APOE ε4 genotyping. Our model training cohort, BioFINDER-1 (NCT01208675), recruited...
A comparative study of posterior cingulate metabolism in patients with mild cognitive impairment due...
Mild cognitive impairment (MCI) precedes both Alzheimer’s disease (AD)- and Parkinson’s disease (PD)-associated dementia2,3,4,13. This is the first comparative study to examine metabolic patterns in the PCC (via single voxel 1H-MRS) between these two...
Hippocampal subfield vulnerability to α-synuclein pathology precedes neurodegeneration and cognitive dysfunction
Goedert, M., Spillantini, M. G., Tredici, K. D. & Braak, H. 100 years of Lewy pathology. Nat. Rev. Neurol. 9, 13 (2013).Article
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α-Synuclein pathology in post-mortem retina and optic nerve is specific for α-synucleinopathies
London, A., Benhar, I. & Schwartz, M. The retina as a window to the brain-from eye research to CNS disorders. Nat. Rev. Neurol. 9, 44–53 (2013).Article
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A Dementia mortality rates dataset in Italy (2012–2019)
Data sourceRaw data used for the computation of SMR were collected on the Italian National Institute of Statistic website (ISTAT, http://www.istat.it/en/, last access: 26/01/2023) for a time window of 8 years (2012–2019). ISTAT is...