Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER...
Jump to Section1. Background2. Methods 2.1. Study participants 2.2. Measures 2.2.1. Neuropsychological evaluation 2.2.2. NIH-EXAMINER 2.2.3. FTLD-specific Clinical Dementia Rating scale 2.3. Genetic testing 2.4. Neuroimaging 2.5. Statistical analysis3. Results 3.1. Demographics, genetic, and clinical characteristics 3.2. Group differences in neuropsychological performances 3.3. Sample size...
Mouse brains, human microglia | Nature Reviews Neurology
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UCSF Diagnostic Radiology Residency Program is a Top-Ranked Program According to Doximity (Again)!
The following article was written by Soonmee Cha, MD, professor in residence of Radiology and Neurological Surgery, vice chair of Education, Diagnostic Radiology residency program director and Integrated Interventional Radiology residency...
Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with...
Jump to Section1. Background2. Methods 2.1. Subjects 2.1.1. GR@ACE cohort and phenotype definitions 2.1.2. Replication sample 2.2. GWAS genotyping, quality control, imputation, and statistical analysis 2.3. Genetic exploration of GR@ACE clinical endophenotypes and enrichment analysis 2.4. Meta-analysis: Data sets and...
Genetic predisposition, modifiable-risk-factor profile and long-term dementia risk in the general population
1.van der Lee, S. J. et al. The effect of APOE and other common genetic variants on the onset of Alzheimer’s disease and dementia: a community-based cohort study. Lancet Neurol. 17, 434–444 (2018).2.Kunkle, B....
UCSF Health Radiology Team Members Receive 2019 PRIDE Awards
Two UCSF Radiology team members, Ricky Ng, RT, radiologic technologist and Gerard Phillips, interventional radiology nurse, were acknowledged with PRIDE Awards at the fifth annual UCSF Health Evening of Honors...
A deep learning model for early prediction of Alzheimer’s disease dementia based on hippocampal...
Fig. 2Mean AD-like relevance maps for different subject groups, demonstrating the discriminative subregions that distinguish AD from NC subjects and characterizing the imaging patterns along the progression of AD dementia. Warmer color indicates severer brain...
Genetic predisposition and modifiable risks for late-life dementia
Genetic predisposition and modifiable risks for late-life dementia
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Objective napping, cognitive decline, and risk of cognitive impairment in older men
Fig. 1Multivariable∗-adjusted ORs (95% CI) of cognitive impairment by napping duration; ∗Adjusted for age, education, BMI, smoking, physical activity, depressive symptoms, history of stroke, coronary heart disease, hypertension, diabetes, sleep medication use, and baseline 3MS...
Neuroinflammation in frontotemporal dementia | Nature Reviews Neurology
1.Hodges, J. R. & Miller, B. The classification, genetics and neuropathology of frontotemporal dementia. Introduction to the special topic papers: part I. Neurocase 7, 31–35 (2001).2.McKhann, G. M. et al. Clinical and pathological diagnosis...