Participants
We used the data from five longitudinal multicenter cohorts: the ADNI25,26,27,28,29,30,31 (N = 1652), the Australian imaging, biomarker, and lifestyle flagship study of aging (AIBL)32,33 (N = 460), the JJ-ADNI34,35 (N = 470), the PharmaCog cohort36,37 (N = 111) and the MEMENTO cohort38 (N = 1994).
The study protocols were approved by the ethical committees of the university of southern California (ADNI), Austin Health, St Vincent’s Health, Hollywook Private Hospital and Edith Cowan University (AIBL), IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli (PharmaCog), Comité de protection des personnes sud-ouest et outre-mer III (MEMENTO), the National Bioscience Database Center Human Database (J-ADNI). Informed consent forms were obtained from research participants. The research has been performed in accordance with the Declaration of Helsinki…
