Study population
The BioFINDER study was approved by the Regional Ethics Committee in Lund, Sweden (case number 2014/223), and all participants gave their written informed consent to participate in the study. Samples for the validation cohort were collected as part of a phase 3 clinical trial conducted in accordance with the Declaration of Helsinki for experiments involving human research. All participants gave their informed consent to participate in the study.
BioFINDER cohort
Cognitively unimpaired controls (n = 65) and patients with MCI43 (n = 29), AD dementia44 (n = 43), PD45 (n = 10), PDD46 (n = 17), PSP47 (n = 6), DLB48 (n = 7), CBS49 (n = 7) and FTD50,51 (n = 10) were recruited from the Swedish BioFINDER study. All participants underwent a medical history, complete neurologic examination, neuropsychological testing and LP. Two LPs were…
