New PET tracer detects hallmark of Alzheimer’s disease years before symptoms emerge

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dementianews
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New PET tracer detects hallmark of Alzheimer's disease years before symptoms emerge
Tau accumulation over one year measured in composite A) mesial temporal ROI; and B) temporoparietal ROI in cognitively unimpaired participants (blue) and cognitively impaired participants (red). The CI group included participants with clinical mild cognitive impairment and dementia. Higher rates of tau accumulation were observed in participants on the AD continuum (CU Aβ+ve and CI Aβ+ve). Participants with the highest baseline tau and rates of tau accumulation were younger and more likely to be CI Aβ+ve. Credit: N Krishnadas et al. Florey Department of Neurosciences & Mental Health, The University of Melbourne; Department of Molecular Imaging & Therapy, Austin Hospital, Melbourne.

A novel positron emission tomography (PET) radiotracer has been shown to effectively measure increases in…

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