A University of California, Irvine-led team of researchers have discovered that the oldest-old, those who live to be 90+ and have superior cognitive skills, have similar levels of brain pathology as Alzheimer’s patients, however, they also have less brain pathology of other neurodegenerative diseases that cause memory and thinking problems.
The study, “Superior Global Cognition in Oldest-Old is Associated with Resistance to Neurodegenerative Pathologies: Results from the 90+ Study,” was published in the Journal of Alzheimer’s Disease.
“People who are 90+ and still have good memory and thinking abilities tend to have similar levels of Alzheimer’s pathology in their brains,” Roshni Biswas, post-doctoral scholar with The 90+ Study. “Our findings indicate that while Alzheimer’s Disease neuropathological changes and vascular changes are common in their brains, these individuals are less…