Newswise — Irvine, Calif., Feb. 15, 2022 – In a scientific first, researchers at the University of California, Irvine have discovered fundamental mechanisms by which the hippocampus region of the brain organizes memories into sequences and how this can be used to plan future behavior. The finding may be a critical early step toward understanding memory failures in cognitive disorders such as Alzheimer’s disease and other forms of dementia.
Combining electrophysiological recording techniques in rodents with a statistical machine learning analysis of huge troves of data, the UCI researchers uncovered evidence suggesting that the hippocampal network encodes and preserves progressions of experiences to aid in decision-making. The team’s work is the subject of a paper published recently in Nature Communications.
“Our brain keeps a pretty good record of when specific experiences…
