High fat diet impairs new neuron creation in female mice

High fat diet impairs new neuron creation in female mice
Female mice on the high fat diet displayed fewer developing neurons in the hippocampus. Credit: Robison et al., eNeuro 2019

A high fat diet limits the birth and growth of new neurons in adult female, but not male, mice, according to new research published in eNeuro. Further research could inspire metabolism-based preventions and treatments for brain disorders.

Metabolic disorders like obesity and type 2 diabetes are associated with an increased risk for brain disorders ranging from depression to Alzheimer’s disease. The birth and development of new neurons—adult neurogenesis—may be a link between these two types of conditions. The hippocampus, an area of the brain implicated in memory and…

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