Researchers introduce into human cells a genetic mutation that protects against Alzheimer’s disease

Alzheimer's disease
Credit: Pixabay/Pete Linforth.

Researchers from the Université Laval Faculty of Medicine and CHU de Québec–Université Laval Research Center have successfully edited the genome of human cells grown in vitro to introduce a mutation providing protection against Alzheimer’s disease. The details of this breakthrough were recently published in The CRISPR Journal.

“Some increase the risk of developing Alzheimer’s disease, but there is a mutation that reduces this risk,” says lead author Professor Jacques-P. Tremblay. “This is a rare mutation identified in 2012 in the Icelandic population. The mutation has no known disadvantage for those who carry…

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