A team of researchers led by the National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN) and Osaka University established a new method to measure glomerular filtration rate (GFR), a primary kidney function, by calculating the clearance of D-serine.
The research group evaluated the clearance of D-serine when assessing GFR through the inulin clearance measurement in living kidney transplant donors and recipients. Consequently, they found that the D-serine clearance strongly correlated with GFR and was less biased than the creatinine clearance, a conventional marker for renal function.
Chronic kidney disease is a global problem, and its frequency is increasing with the aging population. Evaluation of GFR is essential for better clinical practice to reduce the number of dialysis patients; however, the current evaluation of GFR has several limitations, including a…
