Treatment with a bile acid derivative known as TUDCA (tauroursodeoxycholic acid) can mitigate metabolic abnormalities associated with Alzheimer’s disease, such as alterations in food intake and body weight, improving the patient’s quality of life, according to the findings of a study conducted at the University of Campinas (UNICAMP) in the state of São Paulo, Brazil.
Experiments with mice showed that TUDCA combats these metabolic abnormalities by reducing food intake and increasing energy expenditure, as well as improving respiratory quotient, an indicator of metabolic efficiency based on the body’s use of carbohydrates, proteins and…
