‘Live’ brain models used in hunt for Alzheimer’s treatment

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dementianews
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'Live' brain models used in hunt for Alzheimer's treatment
Fig. 1: Senescence-related changes in human cortical brain organoids. a Representative images of sections of human cortical brain organoids derived from H9-ESCs cultured over 13 weeks in vitro and stained with SA-β-gal. Scale bar = 1000 µm. Dotted box indicates a magnified image. W is week. b Quantification of the percentage of SA-β-gal area normalized to the total area of each individual organoid derived from H9-ESCs. Data are presented as mean ± standard deviation. ****P 

Studying tiny ‘live’ models of the human brain has helped researchers understand its aging and find a key to potential treatments for Alzheimer’s and other neurodegenerative diseases.

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