Signals from muscle protect from dementia

Signals from muscle protect from dementia
Research in the lab of Fabio Demontis, PhD, of Developmental Neurobiology, used immunostaining and confocal microscopy on fruit fly brain and retina cells to show that Amyrel reduces the accumulation of protein aggregates seen in red and yellow. Credit: St. Jude Children’s Research Hospital

How do different parts of the body communicate? Scientists at St. Jude are studying how signals sent from skeletal muscle affect the brain.

The team studied and cutting-edge brain cell models called organoids. They focused on the signals muscles send when stressed. The researchers found that stress signals rely on an enzyme called Amyrel amylase and its…

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