Newswise — LEXINGTON, Ky. (Oct. 8, 2021) — A recently released paper from the Department of Physiology and Sanders-Brown Center on Aging (SBCoA) at the University of Kentucky College of Medicine suggests that your genetics can influence your response to Alzheimer’s disease pathology.
The laboratory of Donna Wilcock, Ph.D., professor in the Department of Physiology and SBCoA associate director, investigated inflammation in human brain tissue from UK’s Alzheimer’s Disease Research Center. Brain tissue was analyzed from individuals with different forms of the genetic risk factor, apolipoprotein E (ApoE).
ApoE comes in various forms including ApoE2, ApoE3 and ApoE4. ApoE2 is typically thought of as “protective” and reduces the risk of developing Alzheimer’s disease. ApoE3 is the most common form of the gene, while ApoE4 increases the risk and severity of…
