Protein tangles linked with dementia seen in patients after single head injury

Protein tangles linked with dementia seen in patients after single head injury
These scans show the amount of tau protein in the brains of patients who have suffered a traumatic brain injury. Red represents increased tau accumulation. Credit: Imperial College London

Scientists have visualised for the first time protein ‘tangles’ associated with dementia in the brains of patients who have suffered a single head injury.

This is the finding of a new study led by scientists from Imperial College London, published in the journal Science Translational Medicine.

In the early-stage study, researchers studied 21 patients who had suffered a moderate to severe at least 18 years earlier (mostly from traffic accidents), as well as 11 healthy individuals who had not experienced a…

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