Data resource
The dataset used in this study was derived from the National Health Insurance Research Database (NHIRD) in Taiwan, which covers approximately 99% of the entire population of 23 million people in Taiwan. The Longitudinal Health Insurance Database (LHID) includes all original claims data and registration files from 2000 to 2013 for one million individuals randomly sampled from the Registry for Beneficiaries of the NHIRD program in 2000 in Taiwan. This database has been validated by several studies11,12,13, to prove the correct coding of different diseases. This study was approved by the Institutional Review Board of China Medical University and the Hospital Research Ethics Committee (IRB permit number: CMUH-104-REC2-115) and is in compliance with institutional guidelines. Written informed consent from patients was waived due to low risk, and the study was approved by the…
