Distinct tau PET patterns in atrophy-defined subtypes of Alzheimer’s disease

We used a clustering method to in vivo replicate neuropathologically established subtypes of AD based on atrophy in medial temporal, posterior, and frontal brain regions of 260 patients who are Aβ-positive with prodromal AD or AD dementia and tested whether they differed on tau PET, WMH burden, and rate of cognitive decline. We…

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