Research into Alzheimer’s disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients’ brain tissue, a pathological form of the tau protein contributes to propagating the disease in the brain.
In new research from their joint laboratory, Judith Steen, Ph.D., and Hanno Steen, Ph.D. show for the first time that this pathological tau protein changes its forms over time, which could mean it will take multiple drugs to target it effectively.
For years, pharmaceutical companies have largely focused with very limited…
