Study finds modifiable risk factors could play a role in Alzheimer’s disease

UCI-led study finds modifiable risk factors could play a role in Alzheimer's disease
Study co-author and UCI Down Syndrome expert Dr. Ira Lott examines ABC-DS participant Jeremy Throckmorton. Credit: UCI School of Medicine

Amyloid is a key feature of Alzheimer’s disease, but the accumulation of these sticky proteins may not be the only risk factor for developing Alzheimer’s disease, according to a new study published this week. Other, modifiable risk factors, such as the amount of fats in our blood and how efficiently our bodies generate energy could also play important roles.

One of the largest studies of Alzheimer’s disease (AD) in people with Down Syndrome (DS-AD), this study revealed metabolic alterations in DS-AD are similar to those seen in late onset Alzheimer’s disease (LOAD)…

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