Plasma levels of tau phosphorylated at residue 181 (P-tau181) are a marker of Alzheimer disease (AD), according to two new studies published in Nature Medicine. The measure could form the basis of a diagnostic blood test for AD that would transform clinical practice and AD drug development.
Credit: Association between serum P-tau181 and tau-PET; the more red areas indicate a stronger correlation between tau-PET signal and serum P-tau181. Adapted with permission from Janelidze, S. et al. Nat. Med. https://doi.org/10.1038/s41591-020-0755-1 (2020), Springer Nature Limited.
Currently, a biomarker-supported diagnosis of AD can only be obtained…
