Researchers design proteins that can be utilized to combat Alzheimer’s disease

NYUAD researchers design proteins that can be utilized to combat Alzheimer's disease
NYUAD researchers have developed small proteins called cell-penetrating peptides (CPPs) that prevent the aggregation of the Aβ protein. Credit: NYUAD / Magzoub Lab

A team of researchers, led by NYU Abu Dhabi Assistant Professor of Biology Mazin Magzoub, has developed small proteins called cell-penetrating peptides (CPPs) that prevent the aggregation of the amyloid-β (Aβ) protein associated with Alzheimer’s disease.

There is a growing interest in the use of proteins to develop treatments because they are biocompatible, biodegradable, and can selectively bind to specific targets, which reduces the potential for toxicity. Other pharmaceutically-desirable properties of proteins include greater chemical…

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