For the first time, using a mouse model of Alzheimer’s disease, scientists have documented a link between raised levels of calcium in mitochondria and neuronal death in the living brain. This relationship was previously documented in cell culture, but seeing this phenomenon in living mice makes it more likely that this occurs in people also and could point to a new target for Alzheimer’s disease.
“We were able to show mitochondrial calcium dysregulation in the neurons of living mice with Alzheimer’s-like symptoms using cutting edge live imaging…
