Scientists identify protein associated with ovarian cancer that exacerbates neurodegeneration in Alzheimer’s

Newswise — Houston Methodist scientists identified a protein found in ovarian cancer that may contribute to declining brain function and Alzheimer’s disease, by combining computational methods and lab research.

“Our finding suggests another known protein may be coming into play here, which could help us identify a new therapeutic target one day,” said Stephen T.C. Wong, Ph.D., lead author and Associate Director of Bioinformatics and Biostatistics Cores at Houston Methodist Cancer Center. “These findings may suggest a different role of the protein amyloid beta in neurodegeneration. Many Alzheimer’s researchers have focused on amyloid beta alone, or connections between amyloid beta and another protein, tau.”

In a study…