Researchers uncover epigenetic drivers for Alzheimer’s disease

alzheimers
Credit: Unsplash/CC0 Public Domain

New findings suggest that late-onset Alzheimer’s Disease is driven by epigenetic changes—how and when certain genes are turned on and off—in the brain. Results were published today in Nature Genetics.

Research led by Raffaella Nativio, Ph.D., a former research associate of Epigenetics, Shelley Berger, Ph.D., a professor of Genetics, Biology and Cell and Developmental Biology and Director of the Epigenetics Institute, and Nancy Bonini, Ph.D., a professor of Biology and Cell and Developmental Biology, all in the Perelman School of Medicine at the University of Pennsylvania, used post-mortem brain tissue to compare healthy…

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