Fig. 1
Pairwise comparisons of NF-L, Ng, 14-3-3, and YKL-40 CSF biomarkers. Scatterplots displaying CSF NF-L, Ng, 14-3-3, and YKL-40 concentrations. (A) In neurodegenerative diseases Ctrl, n = 50; AD dementia, n = 108; FTD, n = 50; and CJD, n = 38. (B) In AD continuum Ctrl, n = 50; Preclinical AD, n = 21; MCI due to AD, n = 56; and AD dementia, n = 108. The middle line shows the median. The lower and upper lines correspond to interquartile range. The differences between the groups were assessed using generalized lineal models adjusting for age and gender. A P value <.05 was considered statistically significant. *P < .05, **P < .01, ***P < .001. Abbreviations: NF-L, neurofilament light; Ng, neurogranin; 14-3-3, 14-3-3 g; Ctrl, healthy control subjects; AD, Alzheimer’s disease dementia; CSF, cerebrospinal fluid; MCI, MCI due to AD; FTD, frontotemporal dementia; CJD,…
