Subjects
The study cohort included 27 HC, 26 patients with MCI, and 27 patients with dementia recruited at Osaka University Hospital. Physicians specialized in geriatric medicine and dementia assessed all participants. All subjects underwent standard physical and neurological examinations, neuropsychological assessments, and brain MRI scans within six months of the eye-tracking evaluation. Subjects with MCI and dementia underwent standard blood tests to rule out other disorders that may cause cognitive impairment, such as thyroid disorder or vitamin deficiencies. The patients with MCI met the revised Petersen criteria34, and the patients with dementia met the dementia criteria defined by the DSM-IV35. For the HC group, we recruited individuals who had no active neurologic or psychiatric diseases, with normal cognitive function, an MMSE score between 25 and 30, and a CDR score of 0….
