A scientific strategy that explores therapeutic targets based on the biology of aging is gaining ground as an effective approach to prevent and treat Alzheimer’s disease, according to research published in the December 7, 2018 online issue and the January 8, 2019 print issue of Neurology®.
A comprehensive review of the clinical trial landscape, including current agents being studied for the prevention and treatment of Alzheimer’s disease (and other dementias), points to the need to develop and test drugs based on an understanding of the multiple effects of aging on the brain.
“Alzheimer’s is a complex disease with many different factors that contribute to its onset and progression,” says Dr. Howard Fillit, founding executive director and chief science officer of the Alzheimer’s Drug Discovery Foundation (ADDF), senior author of the review paper. “Decades of…
