Gene linked to Alzheimer’s disease is involved in neuronal communication

Gene linked to Alzheimer's disease is involved in neuronal communication
The corresponding author of this work: Dr. Joshua Shulman. Credit: Baylor College of Medicine

A study published today in the journal Cell Reports sheds new light on how the CD2AP gene may enhance Alzheimer’s disease susceptibility. Integrating experiments in fruit flies, mice and human brains, a multi-institutional team led by researchers at Baylor College of Medicine found that the CD2AP gene is involved in synaptic transmission, the process by which neurons communicate. Digging deeper, the researchers discovered that CD2AP affects neuronal communication by regulating the levels of key regulatory proteins present at neuron terminals (synapses).

Dr. Joshua Shulman, associate professor of…

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