Abnormal deposits of the protein amyloid beta in the brain have been linked to Alzheimer’s disease. The above illustration reveals a potential way discovered by UTSW researchers to stop this process, leveraging the protective nature of the protein transthyretin (TTR) to identify a segment of this protein, TTR-S, that halts plaque formation and facilitates its degradation in a test tube. Credit: UT Southwestern Medical Center
A protein that wreaks havoc in the nerves and heart when it clumps together can prevent the formation of toxic protein clumps associated with Alzheimer’s disease, a new study led by a UT Southwestern researcher shows. The findings, published recently in the Journal of Biological Chemistry, could lead to new treatments for this brain-ravaging condition, which…
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